Cardiovascular disease is a serious public health problem, responsible for vast numbers of hospitalizations and deaths each year. The costs of treatment--including drugs and invasive procedures--have increased dramatically, indicating an urgent need for the development of prevention and treatment measures for atherosclerosis. In order to develop effective treatments and prevention strategies, potential causes of atherosclerosis must be addressed. Recent research has marked the distinct possibility that homocysteine may play an important role in the presence and progression of atherosclerosis (van den Bosch et al., 2003; Aronow, 2003; Geisel et al., 2003; Lawrence de Koning et al., 2003; Hackham & Anand, 2003; Stuhlinger et al., 2003). Homocysteine is an amino acid found in the blood in different concentrations. Evidence has indicated that increased levels of homocysteine in the blood are associated with a higher risk of cardiovascular disease, especially atherosclerosis.
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